A New Option for Treatment-Resistant Depression—Covered by Insurance

Spravato® (esketamine) nasal spray is an FDA-approved treatment for adults with treatment-resistant depression, offered in a safe, supervised clinical setting at Bluewater Psychiatry.

Free Discovery Call

You May Be a Candidate for Spravato If…

A brief discovery call can help determine if Spravato® may be right for you.



You’ve tried multiple antidepressants without lasting relief



Depression is affecting your work, relationships, or daily life



You feel stuck, numb, or exhausted by the cycle of medications



You want a treatment that works differently than traditional antidepressants

What is Spravato®?

Spravato® is a prescription nasal spray derived from ketamine and FDA-approved for treatment-resistant depression. Unlike traditional antidepressants that work on serotonin, Spravato® targets NMDA receptors in the brain, helping restore neural connections linked to mood and emotional regulation.

Why Spravato® is Different



Alternative Approach

Targets glutamate pathways, not serotonin



Fast Relief

Some experience improvement within weeks



FDA-Approved

An evidence-based and research backed treatment



Comprehensive Solution

Used alongside your current treatment plan

What to Expect During Treatment

Our team is experienced, compassionate, and focused on your safety and comfort every step of the way.



01. Free Discovery Call

Discuss eligibility and answer questions



02. Psychiatric Evaluation

Discuss symptoms, history, and treatment options



03. In-Office Treatment Sessions

Comfortable, supervised environment



04. Observation & Support

You relax while we monitor your safety



05. Ongoing Care

The follow-up you need

Our free ebook explains depression and anxiety, why traditional treatments don’t work for everyone, and how newer therapies may offer hope.

Why Bluewater Psychiatry?



Compassionate psychiatric providers



Evidence-based, research backed personalized care



Spravato provided in a calm, private clinical environment



Dedicated support from first call to follow-up

Frequently Asked Questions About Spravato

Is Spravato® safe?

Spravato® is FDA-approved for adults with treatment-resistant depression and has been studied extensively in clinical trials.

At Bluewater Psychiatry, Spravato® is administered in-office only under medical supervision. Our team monitors you before, during, and after each session to ensure your safety and comfort.

Like all treatments, Spravato® can have side effects, which will be discussed with you in detail before starting care.

Will I feel “high” or out of control?

Some patients experience temporary sensations such as lightheadedness, dissociation, or feeling “different” during treatment. These effects are expected and typically wear off within a couple of hours.

You remain in a calm, supervised environment throughout your visit, and a provider is always available if you need support. Most patients describe the experience as manageable and feel back to themselves by the end of the observation period.

How long does treatment take?

Each Spravato® appointment typically lasts about two hours, which includes:

Medication administration
A required observation period
Monitoring by our clinical team

Treatment usually begins with twice-weekly sessions for a short period, followed by less frequent maintenance visits if the treatment is effective. Your exact schedule will be personalized based on your response and clinical needs.

Do I need someone to drive me home?

Yes. Because Spravato® can cause temporary drowsiness or altered perception, you will need a ride home after each treatment session.

Patients are not permitted to drive themselves or use rideshare services alone. We’ll review these requirements with you ahead of time so you can plan comfortably.

How do I know if I qualify for Spravato®?

You may be a candidate for Spravato® if:

You have been diagnosed with treatment-resistant depression
You’ve tried two or more antidepressants without sufficient relief
You are able to receive treatment in a supervised clinical setting
You have suicidal ideation

The best way to find out is through a free Discovery Call. During this call, we’ll review your history, answer questions, and verify insurance coverage—no pressure or commitment required.